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(124) used a methylglyoxal-induced muscle dysfunction model in mice, where oxidative stress, inflammation, and protein degradation contribute to muscle loss and functional decline

This process requires plenty of water

OPA1 mutations induce mitochondrial DNA instability and optic atrophy plus phenotypes

By blocking FcRn-mediated IgG rescue from lysosomal degradation, these agents lower circulating pathogenic IgG autoantibody titers without broadly suppressing immune cells [26]

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Tetrathiomolybdate induces doxorubicin sensitivity in resistant tumor cell lines