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Description

They are one autoimmune story told across two organs

It has been proposed that ATXN3 is also degraded through autophagy [83], being the mutant (soluble) protein more prone to autophagic degradation, as no changes in endogenous wild-type ATXN3 levels were observed in drug-induced autophagy activation in vivo [84]

Switching to a steroid with less flushing risk might help

Symptoms that do not improve with over-the-counter treatments

Funding The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article

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