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[DOI] [PubMed] [Google Scholar] 107.Smeland OB, Meisingset TW, Borges K, Sonnewald U

A study found a 47% prevalence of anxiety in children with CVS.11 In adults, the prevalence of anxiety varies widely, from 15% to 84%, and was significantly associated in a multivariate analysis.61,62 Similarly, up to 78% of adults with CVS have been reported to present with mild-to-severe depression.62 Although the direct pathophysiologic mechanisms of anxiety or depression in CVS remain nuclear, the elevated incidence of these disorders suggests that emotional regulation plays an important role in the pathophysiology and development of CVS

Cell Biochem.Funct

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(PubMed) Tarantini G, Scrutinio D, Bruzzi P, Boni L, Rizzon P, Iliceto S

*Correspondence: Roberto Badaro, [email protected];[email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers