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42,43 We adjusted for the following: age

Positive effects in IBD and colitis models

Nutrient Interactions Requires B6, B12, and folate for proper conversion to cysteine Low vitamin status risk of hyperhomocysteinemia Interacts metabolically with: Cysteine Glutathione Taurine Choline (via methylation pathways) Adverse Reactions / Side Effects Adverse effects typically arise from overall PN therapy , not methionine specifically

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