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When folic acid is ingested into the human body, it needs to be hydrolyzed into monoglutamic acid by intestinal -glutamyl hydrolase and then absorbed by small intestinal epithelial cells

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This binding mode is similar to how other cationic compounds interact with the MET channel

Most women get the recommended daily amount 2.4 micrograms (mcg) for most adults, 2.6 mcg for pregnant women, and 2.8 mcg for women who are breastfeeding in their diets