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North central cancer treatment group phase I trial N057k of everolimus (Rad001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme

Through transnitrosation, the low-pKa active-site thiol (Cys32) for Trx becomes S-nitrosated, leaving behind a low-molecular weight or protein thiol

Our robust methodology ensured the reliable and reproducible detection of subtle changes in erythrocyte glutathione levelscritical for evaluating intervention efficacy