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Crush injury leads to axonal damage without physical disruption of connective tissue sheaths and is therefore characterized by a spontaneous and fast regeneration

Guo R, Xu W, Wang Y, Yue L, Huang S, Xiu Y, et al

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Nevertheless, achieving therapeutic efficacy with AAV often requires high viral titers, raising potential issues of dose-dependent cytotoxicity, immune responses, and eventual transgene silencing (179)

With good skincare, a healthy diet and most importantly daily sun protection, results can last several months to around a year

Heman-Ackah 2015