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Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals

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For pernicious anemia, lifelong B12 supplementation, often via injections, is standard

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[1] People who regularly take medications that suppress stomach acid for conditions like gastroesophageal reflux disease (GERD) or peptic ulcer diseasesuch as proton-pump inhibitors, H2 blockers, or other antacidsmay have difficulty absorbing vitamin B12 from food