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Proc South Thorac Surg Assoc, 1997

[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing

The systematic review of various evidence and studies suggests that a higher dietary intake of B vitamins could lower the risk of advanced macular degeneration

10.1093/jac/dkw024 54 Dalet-BelucheI.BoulencX.FabreG.MaurelP.BonfilsC

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