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Moreover, its shortcomings have been linked to disturbed homocysteine metabolism, which is associated with various conditions including cancer and cardiovascular disease [52, 53]

Therefore, the purpose of this scoping review is to characterize the current evidence base for peptide therapies relevant to musculoskeletal care, with emphasis on BPC-157, thymosin beta-4 derivatives, and related agents, and to define safety considerations and perioperative implications for orthopaedic surgical patients, including those undergoing TJA

10.1016/j.juro.2015.01.086 74 HansenH

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It is difficult to draw conclusions based on human clinical experience due to a number of variables