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In the context of Alzheimer's disease (AD), both microglia and neighboring neural cells display a range of mitochondrial abnormalities, including: Genetic instability: The accumulation of mitochondrial DNA (mtDNA) mutations with age, which can trigger inflammation by acting as damage-associated molecular patterns (DAMPs)

H., Wu C

The arrays were scanned using an Agilent G2505C scanner and the fluorescence intensity was analyzed with Agilent Feature Extraction software (version 11.0.1.1)

Physiol Rev 82:4795 Bedard K, Krause KH (2007) The Nox family of ROS-generating NADPH oxidases: physiology and pathophysiology

However, there is a notable lack of formal safety data