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doi: 10.1371/journal.pone.0167236

Inhibiting Hv1 channel in peripheral sensory neurons attenuates chronic inflammatory pain and opioid side effects

(2001) Continuous stimulation by normal luminal bacteria is essential for the development and perpetuation of colitis in Tg(26) mice

The goal is to understand whether certain inflammatory pathways can be calmed in specific tissues or disease models without impairing normal host defense