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In a phase 2 dose-finding trial, once-weekly Cagrilintide produced clinically meaningful weight loss about 10.8% at the 4.5 mg dose over 26 weeks with gastrointestinal effects the most common adverse events [1]

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This reflects the therapeutic benefit with killing of tumour cells, but also the acute clinical toxicity of radiotherapy as a consequence of normal tissue cell death

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10.3389/fmed.2021.644594 56 ZhangX.YangS.ChenJ.SuZ