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Description

Pathophysiol 11 (1), 119

Therefore, the HGF/c-Met axis is a key player in cell proliferation, survival and migration and, when dysregulated, can give origin to a variety of cancers

Depending on the treatment objective, it can be administered through subcutaneous injections, oral capsules or drops, food-derived, or topical application

XL184 is being evaluated in a Phase III study in patients with advanced medullary thyroid cancer and in Phase II studies in patients with glioblastomamultiforme and non-small-cell lung cancer that has progressed after previous benefit with erlotinib