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Sexton E, McLoughlin A, Williams DJ, Merriman NA, Donnelly N, Rohde D, et al

Notably, pulmonary tissues lack essential substrates for SCFA biosynthesis (e.g., dietary fiber), and germ-free mouse models exhibit significantly reduced pulmonary SCFA levels - direct evidence that lung SCFAs are entirely dependent on functional gut microbiota-derived interorgan supply (Liu Q

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Favano A., Santos-Silva P., Nakano E., Pedrinelli A., Hernandez A., Greve J

Furthermore, high-throughput compound screening of the ferroptosis pathway identified drug candidates including ferrostatin-1 (Fer-1), a potent inhibitor of lipid peroxidation