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Acute toxicity (dermal): category 1 (0 50 mg/kg), category 2 (LD 50 50 200 mg/kg) and category 3 (LD 50 200 1000 mg/kg) (Winder et al., 2005

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However, host susceptibility is likely to have a relevant impact on the outcome of the studies and in this context, elements of stress and animal strain could have a profound impact on the outcome of the studies (Youdim et al., 2003

While listing all excipients on every strip of medicine may be challenging, the ministry suggested mentioning those causing hypersensitivity on the label