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Console L, Scalise M, Tonazzi A, Giangregorio N, Indiveri C

4.2 Improvement of dysregulated coupling between insulin signaling and lipid metabolism In the context of metabolic diseases, disruption of lipid metabolic homeostasis is frequently accompanied by pronounced insulin resistance

After rats are orally administered with the inclusion complex, its C max is 2.8 times higher than that of pure IH901

[DOI] [PubMed] [Google Scholar] 13.Akerman BR, Lemass H, Chow LM, Lambert DM, Greenberg C, Bibeau C, et al

Mediators Inflamm 2021:5587428

The major difference in the effective dose between the combined and individual treatments not only reveals the efficiency of the combined agents, but also consolidates the notion of optimizing doses of multiple mitochondrial antioxidants/nutrients to effectively and safely prevent PD