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10.1016/S2213-2600(25)00019-0 Summary Keywords dipeptidyl peptidase 1 inhibitors, neutrophil serine proteases, non-cystic fibrosis bronchiectasis, chronic obstructive pulmonary disease, brensocatib, BI 1291583, HSK31858, clinical trials Citation Zhang D, Zhang W, Hu P and Zhang W (2025) Dipeptidyl peptidase 1 inhibitors for inflammatory respiratory diseases: mechanisms, clinical trials, and therapeutic prospects

Group on behalf of the I 201 S, Beck DE, Sweeney WB, McCarter MD

This reinforces the central role of the HFD in defining complex-specific incorporation and essential function, in line with observations in budding yeast (37)

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8 IKK family Amino acid regions (aa 705743) at the carboxyl terminus of IKK and IKK mediate interaction with NEMO

The skin around the injection site will be red, swollen, and painful, potentially accompanied by fever