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Both approaches commonly act on key signaling pathways, including Nrf2, NF-B, and AMPK, indicating a potential for synergistic interaction

However, there are some precautions to consider

Furthermore, our single-cell mass cytometry approach was limited to ~40 proteins, capping the number of metabolic pathways we could interrogate simultaneously

The study planned to include 200 patients with type 2 diabetes who were not on any antidiabetic drugs in the 90 days prior to Visit 1 (except in certain clinical situations, such as acute illness, hospitalization, or elective surgery, short-term (14 days) use of insulin)

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