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J Comp Pathol 172, 31-36

(6) Complex I: Complex I (NADH:ubiquinone oxidoreductase) is a large multiprotein complex located in the mitochondrial inner membrane that accepts electrons from NADH and transfers them to ubiquinone (CoQ 10 ) via FMN and a series of ironsulfur (FeS) clusters, reducing it to ubiquinol (CoQ 10 H 2 ) 68,69

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One trial with 140 middle-aged volunteers showed dose-dependent increases in whole blood NAD+ levels after 8 weeks

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types