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and YD9100002005 to H.Z.), CAS Project for Young Scientists in Basic Research (YSBR-013 to W.X.), CAS Collaborative Innovation Program of Hefei Science Center (2021HSC-CIP003 to W.X.), University Synergy Innovation Program of Anhui Province (GXXT-2022-033 to H.Z.), Research Funds of Center for Advanced Interdisciplinary Science and Biomedicine of IHM (QYZD20230011 to W.X.) and Major Science and Technology Special Projects, Anhui Provincial Department of Science and Technology (202303a07020005 to W.X.)

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No significant heterogeneity was found among RCTs in the diabetic subgroup (I 2 = 0%, P = 0.38), and thus fix-effects model was chosen

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