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Sermorelin Sermorelin is a truncated GHRH analog covering the first 29 amino acids of endogenous GHRH

19 (5), e202100987

Furthermore, the ethical constraints of testing novel therapies in pregnant populations, given potential fetal harm, limit the available translational pathways, exacerbating the gap between preclinical promise and clinical application [68]

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Immunohistochemistry of brain tissues from mice treated with GHK showed evidence of decreased inflammation and increased labeling of histone deacetylase 2, suggesting that in addition to an anti-inflammatory effect, GHK may be triggering an epigenetic pathway in the amelioration of cognitive impairment in aging mice