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10.1007/s10103-014-1670-9 80 TestaiL.MartelliA.FloriL.CiceroA

49 A deficit in the tricarboxylic acid cycle and ETC function under conditions of excessive superoxide production in the brain would be expected to result in a reduced ability to maintain adequate levels of ATP required for normal neuronal and synaptic functioning

However, its different mechanism of action, combined with a favorable safety profile, makes it an option some researchers consider alongside or instead of incretin-based therapies

Nonetheless, despite the lack of an established function of ET, the avid accumulation and retention suggests the importance of this compound, which may help maintain the metabolic activity and protect against potential oxidative damage in tissues

Abakumova, et al

These findings suggest that prebiotic-based UA formulations could improve drug stability and support cancer prevention and therapy