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Arch Neurol 50:3036 Troost D, Van den Oord JJ, de Jong JMBV et al (1989) Lymphocytic infiltration in the spinal cord of patients with amyotrophic lateral sclerosis

( Reference Houglum, Venkataramani and Lyche 59 ) , in a series of six patients with chronic hepatitis C refractory to IFN therapy, showed that treatment with vitamin E inhibited important steps in hepatic fibrogenesis such as stellate cell activation and collagen-1(I) gene expression, suggesting a potential role of this vitamin in preventing hepatic fibrosis, which is a critical step in the progression of HCV-related liver disease

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Discontinue sulfamethoxazole and trimethoprim if a significant electrolyte abnormality, renal insufficiency or reduction in the count of any formed blood element is noted

Increases in plasma conjugated bilirubin lead to tea-colored urine, because conjugated bilirubin is water soluble

Immunotherapies, particularly immune checkpoint inhibitors, have taken the concept of treating cancers to the next level, by targeting the cancer patients immune cells rather than their cancer cells