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For example, in hepatocellular carcinoma (HCC), ferroptosis serves as a tumor-suppressive mechanism in early stages but becomes dysregulated in advanced disease, suggesting that dynamic modulation may be necessary during different phases of neurodegeneration

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69 It was hypothesized that LPS elevates A levels, damages oligodendrocytes, and causes myelin destruction in the AD brain by acting on leukocyte and microglial TLR4-CD14/TLR2 receptors, triggering an NF-kB-mediated rise in cytokines

This underscores the importance of seeking professional guidance when considering such treatments