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88 Nevertheless, RAG-independent activation of mTORC1 by amino acids has been described in both yeast and human cells

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235 H 2 O 2 also increases threonine phosphorylation in Caco-2 cells by downregulating PP2A via oxidation of its redox-sensitive Cys266 and Cys269, forming inhibitory disulfide bonds, 236 particularly through oxidation of the B55 isoform

With the widespread use of antifungal agents, resistance among Candida species has become increasingly concerning, especially with the emergence of multidrug-resistant strains such as Candida auris , now recognized as a global health threat (Clancy and Nguyen, 2016

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