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The study found no significant differences in systemic side effects between routes, but noted that injection site reactions were the leading cause of treatment discontinuation (3% of injectable users versus 1% of oral users discontinuing due to GI upset)

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As with all surgeries, there are possible complications, and patients very rarely (less than 5% of the time) experience facial weakness, numbness, double vision, or decreased hearing

Pernicious Anemia Complications If you don't get treatment for pernicious anemia, you could face the following complications: Higher risk of gastric cancer Fractures in the back, upper leg, and upper forearm Brain and nervous system problems that could become permanent A false-positive Pap smear because a B12 deficiency affects the way certain cells in the cervix look Takeaways Pernicious anemia (PA) is an autoimmune condition where your body cant absorb vitamin B12 and so can't make enough healthy red blood cells

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