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10.1056/NEJMoa2309000 38 HeJ.LongX.NieC.ZhaoX.WangW.ZhuQ

& Strohl, K

Listernick, R., Ferner, R

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Many patients notice a boost in energy and overall well-being within a few hours of receiving their B12 shot, while others may take a few days to feel the full benefits

However, although animal experimentations suggest a link between sleep deprivation and immune dysfunction in neurodegenerative processes, no human investigations have yet confirmed the mediating role of immune dysregulation in the association between sleep deprivation and risk or outcomes of NDDs