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Outinen PA, Sood SK, Liaw PCY, Sarge KD, Maeda N, Hirsh J, Ribau J, Podor TJ, Weitz JI, and Austin RC (1998)

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This severely compromises the neurons capacity to eliminate lipid peroxides, ultimately driving neurons toward ferroptosis (204)

doi: 10.1111/jop.13270 25 BroccolettiR.CafaroA.GambinoA.RomagnoliE.ArduinoP

Data gathered using this blend assists in mapping out biochemical signaling networks without clinical confounding variables

A series of rodent investigations have indicated that a relative dearth or perturbation within the IGF-1/IGF-1R signaling pathway results in an escalation of OS in hippocampal neurons of AD transgenic mice, particularly those bearing the APPswe/PS1E9 mutations (APP/PS1)