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Structurally it is ACTH 4-7 (Met-Glu-His-Phe), the melanocortin core of adrenocorticotropic hormone, extended at the C-terminus with Pro-Gly-Pro

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Activation of Paneth cells in response to intestinal dysbiosis may be responsible for early symptoms of this disease, confirming the existence of an intestinal-articular axis

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10.1073/pnas.77.11.6359

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Follow with Vitamin C body cream for hydration and brightening

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