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SKU: 63780791745
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5.1 Efgartigimod Efgartigimod (also known as ARGX-113) is an IgG1 Fc fragment engineered for strong, less pH-dependent binding to FcRn by the introduction of five amino acid substitutions described as MST/HN [115]

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This effect was evidenced by improved uptake of soluble antigens, elevated expression of genes encoding IL-6, TNF-, iNOS, and IL-1, and a marked increase in nitric oxide production (223, 224)