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Treatment with 32-134D reduced the hypoxia-induced expression of genes associated with tumor metabolism and immune evasion, such as PD-L1, while enhancing the activity of CD8 + IFN- + T cells and NK cells, key players in antitumor immunity [22]

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p median of CBT-PBT, indicating cooler PBT relative to CBT) was associated with increased amplitudes of N3 and REM within sleep cycles (see Suppl

348 Similarly, in human chondrocytes stimulated by TNF, GLP-1 analogs (such as liraglutide) showed an anti-catabolic effect, reducing the mRNA expression of MMP-3, MMP-13, and ADAMTS5