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DHCA and Mal-gluc, as externalizing metabolites of bioactive dietary polyphenol compounds, have been associated with depression [98], and in addition to modulating neurexins and synaptic plasticity, studies on their further sustained antidepressant activity should follow

As a medication, it is often used to treat vitamin B12 deficiency, which can lead to anemia and neurological disorders

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GST, glutathione- S -transferase

Reported adverse reactions include nausea, difficulty breathing, and, in rare cases, serious conditions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and renal dysfunction

It has been the subject of an extensive investigation regarding its bioactive chemicals