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Vegans Research shows that vegans are at higher risk of vitamin B12 deficiency and the British Nutrition Foundation recommends they eat fortified foods as well as considering a B12 supplement to make up any shortfall

Epigenetics 12 , 116 (2020)

In rare cases, high doses of B12 might exacerbate anxiety symptoms due to fluctuations in energy levels

Overdose of B12 can cause anxiety, acne, skin redness, headache, nausea, vomiting, heart stroke, face paralysis, palpitations, facial ruddiness, and insomnia

In the mitochondria, the fats are oxidized into adenosine triphosphate (ATP), the fuel for cells

increased consumption of glutathione and thus lead to a deficiency