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doi:10.1007/s12011-020-02140-9

Additionally, using SIRT1 knockout mice and STAT3 knockout mouse models may provide more conclusive insights into GHKs mechanism of action

Conversely, M2 macrophages demonstrate diminished antigen-presenting capacity, releasing anti-inflammatory cytokines like interleukin (IL)-10 or TGF-, and suppressing immune responses [122]