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For other pancreatic cancer cell lines (Mia PaCa-2 and BxPC-3), higher concentrations of all compounds (~3 x) were required to reduce cell viability to 50% (data not shown)

mRNA vaccines provide flexibility to be modified if any new virus variants may appear

doi: 10.3389/fped.2023.1263836 Received 20 July 2023 Accepted 21 August 2023 Published 12 September 2023 Volume 11 - 2023 Edited by Paul Henderson, University of Edinburgh, United Kingdom Reviewed by Tudor Lucian Pop, University of Medicine and Pharmacy Iuliu Hatieganu, Romania Bin Wang, Shenzhen Childrens Hospital, China Updates Copyright 2023 Jiachen, Paul Kwong Hang, Kenneth Kak Yuen and Vincent Chi Hang

An organism from this list was included in the model if an exact or species-level match was found among the annotated organisms listed in KEGG because we referenced this database to map genes to enzymes to reactions

Based on this result, the expression abundance of transcripts and genes was calculated as read count or Fragments Per Kilobase of transcript per Million mapped reads (FPKM) value per sample

229,230 Neuroendocrine-immune axis Microglia secrete chemokines that disrupt the integrity of the BBB and increase the ability of immune cells to enter the brain parenchyma