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Mechanical study demonstrated that HG reduced phosphorylation of EZH2 on Thr311 by inactivating AMP-activated protein kinase (AMPK), which transcriptionally inhibited peroxisome proliferator-activated receptor (PPAR-) expression to promote the fibroblasts activation and differentiation

Laakso ML, Hatonen T, Stenberg D, Alila A, Smith S

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Research has focused on its effects on telomere elongation, pineal gland melatonin regulation, antioxidant activity, and longevity-related gene expression

Rectal mesalazine should be used for UC owing to higher efficacy[24,35]