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[15] [17] Very early in the process one of the scientists, Mac Hadley, was conducting self-experiments with melanotan II

Rawson RV

Congenital nevus-associated melanomas occur primarily in children under the age of puberty [1] (Figure 1)

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In addition, pigmentation derived from foreign bodies, heavy metal poisoning or drugs may also promote pigmented lesions, which can vary in intensity and extension, and can occur in any sites of the oral cavity

Researchers at the University of Arizona created MT-2 as a potential skin cancer chemopreventive agent the idea being that increased melanin production could protect fair-skinned individuals from UV damage