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The aims were to (i) evaluate the effects of a single low dose (2 g) of a well-characterized kratom product on the pharmacokinetics of dextromethorphan and midazolam in healthy adult participants and (ii) advance the mechanistic understanding of the resulting pharmacokinetic kratom-midazolam interaction using physiologically-based pharmacokinetic (PBPK) modeling and simulation

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

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Gut microbiome, short-chain fatty acids, alpha-synuclein, neuroinflammation, and ROS/RNS: Relevance to Parkinson's disease and therapeutic implications

10.1016/j.neurobiolaging.2004.09.022 30 Beas-ZarateC.Rivera-HuizarS

EvidenceBased Benefits of Fertility IV Therapy Antioxidant intake has been linked to higher quality embryo rates and increased numbers of retrieved oocytes in older women