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10.1002/jcp.27168 168 SamantaD.SemenzaG

Multiple etiological hypotheses have been proposed, including intoxication with mycotoxins or environmental toxins (31, 32), viral infection, and trace element deficiency caused by a monotonous diet lacking minerals or vitamins (32), such as magnesium, iron, or thiamin (Figures 3AC) (33)

Although median levels were numerically lower in SA compared with M/M, there were no differences in BAL fluid GSSG or GSH:GSSG between M/M and SA

Additionally, inflammation and dysbiosis can lead to systemic effects, contributing to chronic conditions like CKD and neuroinflammation (Adesso et al., 2017)