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In preclinical prostate cancer models, Mobilan displayed promising therapeutic efficacy (276).In phase I clinical trial NCT02654938, Mobilan was used intratumorally to treat prostate cancer

4.1.3 Dopamine and norepinephrine Besides 5-HT and GABA, the catecholamine neurotransmitters dopamine and norepinephrine are important in comorbidity pathogenesis

Hepato-protectant (NAC) and ER stress inhibitor (4-PBA) significantly downregulated ER stress markers in the liver compared to the MTX group, as depicted in Figures 6AE

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Thus, the cells relied on the accumulated GSH prior to SSF to relieve the toxicity