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Interestingly, some individuals with low vitamin B12 levels may not show any symptoms

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Management: o Avoid combining with other Vitamin B supplements unless advised by a doctor

Anti-inflammatory nutrition: Omega-3 fatty acids, turmeric/curcumin, and diets rich in colorful fruits and vegetables can support lower systemic inflammation Collagen supplementation: Hydrolyzed collagen provides amino acid building blocks that may support cartilage matrix production Low-impact movement: Swimming, cycling, and walking maintain joint mobility and promote synovial fluid circulation without excessive impact Physical therapy: Targeted exercises prescribed by a physical therapist can improve joint mechanics and reduce pain Safety Considerations AOD-9604 has demonstrated a favorable safety profile in clinical studies

2022;57(14) doi: 10.1016/j.devcel.2022.06.005