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For instance, it was found that intravenously administered 20 nm AuNPs could effectively cross the BRB and reach all of the retinal layers, while 100 nm NPs could not [37]

Leske MC, Wu SY, Hyman L, Sperduto R, Underwood B, Chylack LT, Milton RC, Srivastava S, Ansari N

PC-CARs may also have an advantage over CARs that target membrane proteins in their ability to initiate a feed-forward loop of MHC upregulation and increased antigen density