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However, low-dose IPA (20 mg/kg) administration demonstrated marginal attenuation of disease phenotypes, showing only modest mitigation in pathological indices, mucosal barrier integrity and inflammatory markers that failed to reach statistical significance compared to vehicle-treated controls (Fig

DNA sequences substantially homologous to or derived from native V, D, J, constant, switches and other such sequences described herein are contemplated (where "derived" indicates that a sequence is identical or modified from another sequence)

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8A, C), the number of cells arrested in the G1 phase has increased compared to the control group

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