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These peptides are currently heavily utilized in wellness, longevity, and restorative medicine but have faced regulatory uncertainty regarding their safety and legality

BPC-157 has a large publication count concentrated in tendon, gastrointestinal and angiogenesis models, but the publication count is dominated by a single research group, and the field has been slow to produce independent replication of the largest effect sizes

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At the same time, small for gestational age (SGA) babies becomes insulin resistant (46) and this trait is enforced by a low endocrine IGF-I setpoint (47), creating the best physiological circumstances for the storage of fat during short times of food availability in a world with limited access to food