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The pronounced malignancy of gliomas, particularly GBM, poses a significant therapeutic challenge worldwide

Individuals with irritable bowel syndrome (IBS) exhibit elevated levels of bacteria related to intestinal inflammation, such as Enterobacteriaceae and Streptococcus , while the content of beneficial bacteria (such as Faecal Streptococcus ) decreases (Sciavilla et al., 2021)

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Iron-induced cell death, serving as a trigger, may contribute to the transition from acute kidney injury (AKI) to CKD through sustained oxidative stress and mitochondrial dysfunction