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It is a single small aromatic molecule designed to be membrane-permeable, so in principle it can survive the gut and cross into cells

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Robinson DS, Amsterdam JD

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Within the TME, the interplay between tumor vessels and protumoral immune cells generates a vicious cycle that severely disturbs anti-cancer immunity and promotes tumor progression

doi: 10.1042/CS20171330 58 WirthKScheibenbogenC