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It is more likely to occur in those patients receiving too much of the medicine but can occur with small doses as well

MRM multiple reaction monitoring the 1-MNA NNMT reaction product was quantified from peak area ratios using AB Sciex Analyst and MultiQuant 2.1 software and the parent precursor and Q3 masses set to m/z 137.1 and 94.1, respectively

Comparing costs of intramuscular and oral vitamin B12 administration in primary care: a cost-minimization analysis

doi:10.1016/j.bcp.2019.02.008 Dimet-Wiley A, Latham CM, Brightwell CR, et al

Inositol improves your mood and treats anxiety and depression, along with preventing the hardening of the arteries

If you already have a diagnosed deficiency under NHS care and your symptoms return before your next scheduled dose, that is a conversation to have with your GP, who can review the schedule