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Through allosteric mechanisms, high ATP levels inhibit the activity of the pyruvate dehydrogenase component of the complex, whereas high ADP levels, which signal that the energy charge of the cell may be falling, activate it, thus committing the carbon skeletons of carbohydrates and some amino acids to energy production

The definitive answer is yes, but it absolutely requires the correct context

Hui-Hui Chen, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Oliver BGG

FIGURE 1 3 Environmental and lifestyle drivers of accelerated ovarian aging A growing body of evidence supports the notion that menopause timing is not solely genetically determined but is significantly influenced by lifestyle and environmental exposures