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The DNA encoding the monoclonal antibodies of the invention can be readily isolated and sequenced using conventional procedures (e.g., by using oligonucleotide probes that are capable of binding specifically to genes encoding the heavy and light chains of murine antibodies, or such chains from human, humanized, or other sources)

Ampakine Boosts Performance in the Morris Water Maze for Juvenile and Young Adult Rats

10.1161/CIRCRESAHA.121.320060 141 MeeganJ

We scrutinize the role of ROS from hepatitis onset through liver fibrosis to HCC growth and migration, discussing their impact on cellular fates such as proliferation, phenotype remodeling, senescence, and cell death

Clarified supernatants were filtered using 0.2-m filters, transferred to new 50-ml Falcon tubes containing Ni-NTA resin equilibrated with lysis buffer (20 mM Tris-HCl (pH 9), 10 mM imidazole, 200 mM NaCl and 5% glycerol) and agitated for 1 h to allow protein binding

In vivo research by Matouk et al